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Skip to main content Advertisement Main menu Home Articles Accepted manuscripts Issue in progress Latest complete issue Issue archive Archive by article type Interviews Sign up for alerts About us About BiO Editors and Board Editor biographies Grants and funding Journal Meetings Workshops The Company of Biologists Journal news For authors Submit a manuscript Aims and scope Presubmission enquiries Article types Manuscript preparation Cover suggestions Editorial process Promoting your paper Open Access Journal info Journal policies Rights and permissions Media policies Reviewer guide Sign up for alerts Contact Contact BiO Advertising Feedback COB About The Company of Biologists Development Journal of Cell Science Journal of Experimental Biology Disease Models & Mechanisms Biology Open User menu Log in Search Search for this keyword Advanced search COB About The Company of Biologists Development Journal of Cell Science Journal of Experimental Biology Disease Models & Mechanisms Biology Open Biology Open Search for this keyword Advanced search Home Articles Accepted manuscripts Issue in progress Latest complete issue Issue archive Archive by article type Interviews Sign up for alerts About us About BiO Editors and Board Editor biographies Grants and funding Journal Meetings Workshops The Company of Biologists Journal news For authors Submit a manuscript Aims and scope Presubmission enquiries Article types Manuscript preparation Cover suggestions Editorial process Promoting your paper Open Access Journal info Journal policies Rights and permissions Media policies Reviewer guide Sign up for alerts Contact Contact BiO Advertising Feedback Due to COVID-19, Biology Open staff are working remotely, but our editorial operations continue to run as usual. Please contact us by email at bio@biologists.com if you have any queries. Thank you for your patience and understanding. For more information on measures BiO is taking to support the community at this time, please see here . Archive Biology Open (BiO) is an online Open Access journal that supports the community of biologists through the publication of peer-reviewed original research across all aspects of the biological sciences. We aim to provide rapid peer review and publication of scientifically sound results and conclusions, without a requirement for perceived impact. BiO also aspires to promote a peer-review system that is timely, thorough, constructive and fair. Authors are encouraged to submit work of appropriate scope directly to BiO. Editorial decisions are made by an international board of research-active academic Editors, led by Editor-in-Chief Steven Kelly and supported by Deputy Editors Cathy Jackson and Yishi Jin. Latest complete issue Issue in progress Submit a manuscript Sign up to alerts Accepted manuscripts Most-read Open Access Smoking flies: Testing the effect of tobacco cigarettes on heart function of Drosophila melanogaster Manuela Santalla , Lucía Pagola , Ivana Gómez , Darío Balcazar , Carlos A. Valverde , Paola Ferrero PDF Open Access Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry Hantian Qiu , Sayaka Fujisawa , Shohei Nozaki , Yohei Katoh , Kazuhisa Nakayama PDF Open Access A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference Nina Graffmann , Audrey Ncube , Soraia Martins , Aurelian Robert Fiszl , Philipp Reuther , Martina Bohndorf , Wasco Wruck , Mathias Beller , Constantin Czekelius , James Adjaye PDF Open Access A method to culture human alveolar rhabdomyosarcoma cell lines as rhabdospheres demonstrates an enrichment in stemness and notch signaling Katherine K. Slemmons , Michael D. Deel , Yi-Tzu Lin , Kristianne M. Oristian , Nina Kuprasertkul , Katia C. Genadry , Po-Han Chen , Jen-Tsan Ashley Chi , Corinne M. Linardic PDF Open Access Wound-induced polyploidization is dependent on integrin-yki signaling Rose Besen-McNally , Kayla J. Gjelsvik , Vicki P. Losick PDF See more accepted manuscripts... Recent articles The novel zebrafish model pretzel demonstrates a central role for SH3PXD2B in defective collagen remodelling and fibrosis in Frank-Ter Haar syndrome Ivo J. H. M. de Vos, Arnette Shi Wei Wong, Jason Taslim, Sheena Li Ming Ong, Nicole C. Syder, Julian L. Goggi, Thomas J. Carney, Maurice A. M. van Steensel A novel sh3pxd2b mutant zebrafish model develops cutaneous and musculoskeletal fibrosis, similar to that observed in people with Frank-Ter Haar syndrome. Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission Sebastian M. Markert, Michael Skoruppa, Bin Yu, Ben Mulcahy, Mei Zhen, Shangbang Gao, Michael Sendtner, Christian Stigloher Neuronal expression of an ALS-associated mutation in a DNA/RNA-binding protein disrupts the organization and function of the C. elegans neuromuscular junction. Future Leader Reviews Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research In our most recent Future Leader Review, Fabrizio Alberti and colleagues discuss recent developments with tools for genome and metabolome studies that will facilitate the discovery and characterisation of natural products from fungi of the phylum Basidiomycota. Find out more about Fabrizio and his work in the associated Future Leader to Watch interview. Uncharted routes: exploring the relevance of auxin movement via plasmodesmata In this Future Leader Review, Andrea Paterlini discusses the biological relevance of auxin transport via plasmodesmata in plants. Physical modes of transport of auxin, feedback loops of its movement and evolutionary aspects are included. Find out more about Andrea and his work in the associated Future Leader to Watch interview. News from BiO Highlighted articles Informing epidemic (research) responses in a timely fashion by knowledge management – a Zika virus... Angela Bauch , Johann Pellet , Tina Schleicher , Xiao Yu , Andrea Gelemanović , Cosimo Cristella , Pieter L. Fraaij , Ozren Polasek , Charles Auffray , Dieter Maier , Marion Koopmans , Menno D. de Jong Drosophila MICOS knockdown impairs mitochondrial... Li-jie Wang , Tian Hsu , Hsiang-ling Lin , Chi-yu Fu Overexpression of an ALS-associated FUS mutation in C... Sebastian M. Markert , Michael Skoruppa , Bin Yu , Ben Mulcahy , Mei Zhen , Shangbang Gao , Michael Sendtner , Christian Stigloher Locomotor mechanism of Haplopelma hainanum based... Xin Hao , Wenxing Ma , Chunbao Liu , Zhihui Qian , Luquan Ren , Lei Ren CD47 differentially regulates white and brown fat function Heather Norman-Burgdolf , Dong Li , Patrick Sullivan , Shuxia Wang iPSC-derived hepatocytes generated from NASH donors provide a valuable platform for disease... Igor Gurevich , Sarah A. Burton , Christie Munn , Makiko Ohshima , Madelyn E. Goedland , Katherine Czysz , Deepika Rajesh Chorismate synthase mediates cerebral malaria pathogenesis by eliciting salicylic acid-dependent... Malabika Chakrabarti , Deepika Kannan , Akshay Munjal , Hadi Hasan Choudhary , Satish Mishra , Shailja Singh Harmine enhances the activity of the HIV-1 latency-reversing agents ingenol A and SAHA Jared P. Taylor , Lucas H. Armitage , Daniel L. Aldridge , Melanie N. Cash , Mark A. Wallet MicroRNA-9-5p inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts... Chi-Yung Chai , I.-Chun Tai , Rui Zhou , Junlong Song , Chaoying Zhang , Shengrong Sun The novel zebrafish model pretzel demonstrates a... Ivo J. H. M. de Vos , Arnette Shi Wei Wong , Jason Taslim , Sheena Li Ming Ong , Nicole C. Syder , Julian L. Goggi , Thomas J. Carney , Maurice A. M. van Steensel Journals from The Company of Biologists Articles Accepted manuscripts Issue in progress Latest complete issue Issue archive Archive by article type Intervie...